2022 — Doshisha University, Japan
Eight Weeks of NMN. Signals of Cellular Renewal.
In this eight-week human study, 17 healthy postmenopausal women received 300 mg of NMN daily. Researchers observed positive changes in biomarkers associated with healthy ageing and cellular function. Participants also reported improvements in sleep, fatigue and skin condition, with no safety concerns identified. Together, these findings reinforce the growing promise of NMN in supporting cellular vitality and the body's natural renewal processes.
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2021 – Washington University School of Medicine, USA
NMN Improves Metabolism and Insulin Sensitivity in Women
In a landmark, randomised, double-blind, placebo-controlled study published in the journal Science, postmenopausal women with prediabetes who took 250 mg of NMN daily for ten weeks saw a significant improvement in muscle insulin sensitivity, alongside a marked rise in NAD⁺ levels. The findings reinforce NMN's role in supporting healthy metabolism and sustained vitality through the changes of midlife.
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2024 — Wenzhou Medical University & Zhejiang University School of Medicine, China
NMN Extends Lifespan and Strengthens Gut Health in Preclinical Models
Published in the journal Food & Function, this revealing study found that NMN supplementation extended lifespan in ageing models while protecting intestinal health. By supporting beneficial gut bacteria, reducing inflammation, and reinforcing the intestinal barrier, NMN helped maintain microbiome balance: a key foundation for longevity and immune resilience.
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2024 – Aging & Disease
How NMN Powers NAD⁺ to Slow the Hallmarks of Ageing
This review summarises the mechanisms by which NMN — the body’s natural precursor to NAD⁺ — supports vital systems including energy metabolism, mitochondrial health, inflammation control, and DNA repair. As NAD⁺ levels decline with age, NMN replenishes them, enhancing cellular function and promoting healthy ageing across multiple biological pathways.
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2022 — University of Tokyo, Japan
NMN Supports Strength, Mobility, and Vigour in Older Men
In a pioneering, randomised, double-blind, placebo-controlled study, men aged 65 and over took 250 mg of NMN daily for 12 weeks. NAD⁺ levels rose significantly, alongside meaningful improvements in walking speed and grip strength, with no adverse effects. The findings reinforce NMN's role in preserving strength, mobility, and vigour as the body ages.
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